Biology

Student Learnings: What students should know and be able to do

Concepts in Biology: Understand biological concepts, theories, and principles through investigation and analysis of cells, organisms and ecosystems

Cell Theory

• Structure and Functions of Organelles:
  • Cells have particular structures that underlie their functions. Every cell is surrounded by a membrane that separates it from the outside world. Inside the cell is a concentrated mixture of thousands of different molecules which form a variety of specialized structures that carry out such cell functions as energy production, transport of molecules, waste disposal, synthesis of new molecules, and the storage of genetic material.
• Biochemistry of Cells:
  • Most cell functions involve chemical reactions. Food molecules taken into cells react to provide the chemical constituents needed to synthesize other molecules. Both breakdown and synthesis are made possible by a large set of protein catalysts, called enzymes. The breakdown of some of the food molecules enables the cell to store energy in specific chemicals that are used to carry out the many functions of the cell.
• DNA Expression:
  • Cells store and use information to guide their functions. The genetic information stored in DNA is used to direct the synthesis of the thousands of proteins that each cell requires.
• Regulatory Processes of the Cell:
  • Cell functions are regulated. Regulation occurs both through changes in the activity of the functions performed by proteins and through the selective expression of individual genes. This regulation allows cells to respond to their environment and to control and coordinate cell growth and division.
• Plant Cell Specifics:
  • Plant cells contain chloroplasts, the site of photosynthesis. Plants and many microorganisms use solar energy to combine molecules of carbon dioxide and water into complex, energy rich organic compounds and release oxygen to the environment. This process of photosynthesis provides a vital connection between the sun and the energy needs of living systems.
• Historical Development:
  • Cells can differentiate, and complex multicellular organisms are formed as a highly organized arrangement of differentiated cells. In the development of these multicellular organisms, the progeny from a single cell form an embryo in which the cells multiply and differentiate to for the many specialized cells, tissues and organs that comprise the final organism. This differentiation is regulated through the expression of different genes.

The Molecular Basis of Herdity

• DNA Structure and Function:
  • In all organisms, the instructions for specifying the characteristics of the organism are carried in DNA, a large polymer formed from subunits of four kinds (A, G, C and T). The chemical and structural properties of DNA explain how the genetic information that underlies heredity is both encoded in genes (as a string of molecular "letters") and replicated (by a templating mechanism). Each DNA molecule in a cell forms a single chromosome.
• Patterns of Inheritance (Mendellian Genetics)
• Chromosome Theory of Inheritance:
  • Most of the cells in a human contain two copies of each of 22 different chromosomes. In addition, there is a pair of chromosomes that determines sex: a female contains two X chromosomes and a male contains one X and one Y chromosome. Transmission of genetic information to offspring occurs through egg and sperm cells that contain only one representative from each chromosome pair. An egg and a sperm unite to form a new individual. The fact that the human body is formed from cells that contain two copies of each chromosome—and therefore two copies of each gene—explains many features of human heredity, such as how variation that are hidden in one generation can be expressed in the next.
• Sources/Causes of Genetic Mutations:
  • Changes in DNA (mutations) occur spontaneously at low rates. Some of these changes make no difference to the organism, whereas others can change cells and organisms. Only mutations in germ cells can create the variation that changes an organism's offspring.
• Historical Development:
  • The historical significance of major scientific advances related to the molecular basis of heredity.

The Theory of Biological Evolution

• Species Evolve Over Time:
  • Species evolve over time. Evolution is the consequence of the interactions of (1) the potential for a species to increase its numbers, (2) the genetic variability of offspring due to mutation and recombination of genes, (3) a finite supply of the resources required for life, and (4) the ensuing selection by the environment of those offspring better able to survive and leave offspring.
• Biological Diversity:
  • The great diversity of organisms is the result of more than 3.5 billion years of evolution that has filled every available niche with life forms.
• Natural Selection:
  • Natural selection and its evolutionary consequences provide a scientific explanation for the fossil record of ancient life forms, as well as for the striking molecular similarities observed among the diverse species of living organisms.
• Common Descent:
  • The millions of different species of plants, animals and micro-organisms that live on earth today are related by descent from common ancestors.
• Systematics:
  • Biological classifications are based on how organisms are related. Organisms are classified into a hierarchy of groups and subgroups based on similarities which reflect their evolutionary relationships. Species in the most fundamental unit of classification.
• Historical Development:
  • Understanding the historical significance of major scientific advances related to the theory of biological evolution.

The Interdependence of Organisms

• Matter Cycles:
  • The atoms and molecules on the earth cycle among the living and nonliving components of the biosphere.
• Energy Flow:
  • Energy flows through ecosystems in one direction, from photosynthetic organisms to herbivores to carnivores and decomposers.
• Interrelationships:
  • Organisms both cooperate and compete in ecosystems. The interrelationships and interdependencies of these organisms may generate ecosystems that are stable for hundreds or thousands of years.
• Fecundity:
  • Living organisms have the capacity to produce populations of infinite size, but environments and resources are finite. This fundamental tension has profound effects on the interactions between organisms.
• Human Impact on Ecosystems:
  • Human beings live within the world's ecosystems. Increasingly, humans modify ecosystems as a result of population growth, technology, and consumption. Human destruction of habitats through direct harvesting, pollution, atmospheric changes, and other factors is threatening current global stability, and if now addressed, ecosystems will be irreversibly affected.
• Historical Development:
  • Understand the historical significance of major scientific advances related to the interdependence of organisms.

Matter, Energy and Organization in Living Systems

• Entropy:
  • All matter tends toward more disorganized states. Living systems require a continuous input of energy to maintain their chemical and physical organizations. With death, and the cessation of energy input, living systems rapidly disintegrate.
• Anabolism:
  • The energy for life primarily derives from the sun. Plants capture energy by absorbing light and using it to form strong (covalent) chemical bonds between the atoms of carbon-containing (organic) molecules. These molecules can be used to assemble larger molecules with biological activity (including proteins, DNA, sugars, and fats). In addition, the energy stored in bonds between the atoms (chemical energy) can be used as sources of energy for life processes.
• Catabolism:
  • The chemical bonds of food molecules contain energy. Energy is released when the bonds of food molecules are broken and new compounds with lower energy bonds are formed. Cells usually store this energy temporarily in phosphate bonds of a small high-energy compound called ATP.
• Complexity:
  • The complexity and organization of organisms accommodates the need for obtaining, transforming, transporting releasing, and eliminating the matter and energy used to sustain the organism.
• Limiting Factors:
  • The distribution and abundance of organisms and populations in ecosystems are limited by the availability of matter and energy and the ability of the ecosystem to recycle materials.
• Conservation of Matter and Energy:
  • As matter and energy flow through different levels of organization of living systems—cells, organs, organisms, communities—and between living systems and the physical environment, chemical elements are recombined in different ways. Each recombination results in storage and dissipation of energy into the environment as heat. Matter and energy are conserved in each change.
• Historical Development:
  • Understand the historical significance of major scientific advances related to matter, energy and organization in living systems.

The Behavior of Organisms

• Nervous Systems:
  • Multicellular animals have nervous systems that generate behavior. Nervous systems are formed from specialized cells that conduct signals rapidly through the long cell extensions that make up nerves. The nerve cells communicate with each other by secreting specific excitatory and inhibitory molecules. In sense organs, specialized cells detect light, sound and specific chemicals and enable animals to monitor what is going on in the world around them.
• Stimulus and Response:
  • Organisms have behavioral responses to internal changes and to external stimuli. Responses to external stimuli can result from interactions with the organism's own species and others, as well as environmental changes; these responses either can be innate or learned. The broad patterns of behavior exhibited by animals have evolved to ensure reproductive success. Animals often live in unpredictable environments, and so their behavior must be flexible enough to deal with uncertainty and change. Plants also respond to stimuli.
• Adaptive Behaviors:
  • Like other aspects of an organism's biology, behaviors have evolved through natural selection. Behaviors often have an adaptive logic when viewed in terms of evolutionary principles.
• Human Implications:
  • Behavioral biology has implications for humans, as it provides links to psychology, sociology and anthropology.
• Historical Development:
  • Understand the historical significance of major scientific advances related to the behavior of evolution.

Scientific Inquiry

• Design and conduct experiments.
• Design and conduct an investigation:.
  • Identify scientific issues based on observations and the corresponding scientific concepts.
  • Analyze data to clarify scientific issues or define scientific questions.
  • Compare results to current models and/or personal experience.
• Use scientific evidence to defend or refute ideas in an historical or contemporary context:
  • Identify scientific concepts found in evidence.
  • Evaluate the validity of the idea in relationship to scientific information.
  • Analyze the immediate and long-term impact on the individual and/or society in the areas of technology, ecomonics and the environment.